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Bio-Identical Progesterone

Protect

$55.00 USD Sold out
21 reviews

Bio-Identical Progesterone serum

Fully dissolved, high purity, molecular serum in a vitamin E and MCT oil base for optimal absorption. Derived from wild yams through an enzyme extraction process.

Third-party lab tested for purity.

Supplement Facts

Each bottle contains: 1 oz. (32ml)
Servings per bottle: ~75

Total progesterone per bottle: 2,700 mg.
Progesterone per drop: 3mg

Other ingredients:
Mixed tocopherols, MCT oil.

*Refrigeration not necessary. Stable for 1 year after opening, 3 years if sealed.

Benefits

Stress and anxiety reduction*
Balancing estrogen dominance*
PMS/Hormonal imbalance symptoms*
Brain and memory protective*
Sunburn/sunspots*
Skin firmness & elasticity*
Arthritis*
Tendonitis*
Bursitis*
Wound healing*
Osteoporosis*
Prostate protection*

*These Statements have not been evaluated by the Food and Drug Association, or Health Canada. These products are not meant to diagnose, treat, cure, or prevent any diseases.

How to Take

While we are not 'allowed' to provide medical advice, menstruating women have typically used Protect cyclically, taking 6 drops twice a day orally, only between ovulation and menstruation, and not taking it from menstruation until the next ovulation.
For topical treatment of sun damaged skin, burns, acne, or wrinkles, Protect can be applied directly to the affected area.

We are unable to offer medical advice regarding the usage of progesterone, such as inquiries related to pregnancy, menopause or substituting medications. We recommend that these inquiries be directed to your medical provider for proper guidance and assistance.

Mainly - progesterone is anti-cortisol and anti-estrogen. 

Progesterone is the primary hormone for adaptation and resistance to stress. Adequate amounts of progesterone in the body prevent the excess production of cortisol, one of our primary stress hormones. This is because progesterone inhibits enzymes that increase the production of estrogen, serotonin, and histamine and decreases enzymes that promote excitatory neurotransmitters such as ACTH and NMDA, which can contribute to stress and anxiety.  

Progesterone is primarily associated with the female reproductive system. Its central role revolves around preparing the uterus for pregnancy and supporting early pregnancy development. During the menstrual cycle, progesterone levels rise after ovulation, helping to thicken the uterine lining in anticipation of embryo implantation. If pregnancy doesn't occur, progesterone levels decrease, leading to menstruation. 

However, progesterone is much more than just a hormone that facilitates pregnancy. Having sufficient levels is crucial for resilience from stress, relieving anxiety, improving memory, protecting brain cells, and contributing to bone and skin health. 

Progesterone can also protect against the toxic effects of excess estrogen, leading to symptoms such as acne, stubborn weight gain, depression/anxiety, breast tenderness, cramping, and more, as experienced in PMS, Endometriosis, PCOS, and so forth. 

Progesterone is not only produced in women but is also important in men as it is required for testosterone production, bone health, and prostate health. It protects the overall structure of tissues and prevents their degradation. Progesterone deficiency is less common in men, but supplementation can be helpful in times of increased stress/trauma.

1. Chishti YZ, Feswick A, Martyniuk CJ. Progesterone increases ex vivo testosterone production and decreases the expression of progestin receptors and steroidogenic enzymes in the fathead minnow (Pimephales promelas) ovary. Gen Comp Endocrinol. 2014 Apr 1;199:16-25. doi: 10.1016/j.ygcen.2014.01.004. Epub 2014 Jan 21. PMID: 24462459.

2. Mohammed H, Russell IA, Stark R, et al. Progesterone receptor modulates ERα action in breast cancer [published correction appears in Nature. 2015 Oct 1;526(7571):144. Serandour, Aurelien A A[Corrected to Serandour, Aurelien A]]. Nature. 2015;523(7560):313-317. doi:10.1038/nature14583

3. Stanczyk FZ. Treatment of postmenopausal women with topical progesterone creams and gels: are they effective? Climacteric. 2014 Dec;17 Suppl 2:8-11. doi: 10.3109/13697137.2014.944496. Epub 2014 Sep 6. PMID: 25196424.

4. Smith SS. Progesterone administration attenuates excitatory amino acid responses of cerebellar Purkinje cells. Neuroscience. 1991;42(2):309-20. doi: 10.1016/0306-4522(91)90377-z. PMID: 1654533.

5. El-Etr M, Rame M, Boucher C, et al. Progesterone and nestorone promote myelin regeneration in chronic demyelinating lesions of corpus callosum and cerebral cortex. Glia. 2015;63(1):104-117. doi:10.1002/glia.22736

6. Formby B, Wiley TS. Progesterone inhibits growth and induces apoptosis in breast cancer cells: inverse effects on Bcl-2 and p53. Ann Clin Lab Sci. 1998 Nov-Dec;28(6):360-9. PMID: 9846203.

7. Cowan LD, Gordis L, Tonascia JA, Jones GS. Breast cancer incidence in women with a history of progesterone deficiency. Am J Epidemiol. 1981 Aug;114(2):209-17. doi: 10.1093/oxfordjournals.aje.a113184. PMID: 7304556.

8. MEDICAL TREATMENT OF MALE PATTERN ALOPECIA (ANDROGENIC ALOPECIA)

9. Correction of hormonal imbalance in patients with diffuse forms of mastopathy – the basis of pathogenetic therapy and oncoprophylaxis



10. Brkic, M. , Vujovic, S. , Ivanisevic, M. , Ivovic, M. , Gajic, M. , Marina, L. , Barac, M. , Barac, B. , Djogo, A. , Malesevic, G. and Franic, D. (2016) The Influence of Progesterone Gel Therapy in the Treatment of Fibrocystic Breast Disease. Open Journal of Obstetrics and Gynecology, 6, 334-341. doi: 10.4236/ojog.2016.65042.

11. Topical progesterone cream has an antiproliferative effect on estrogen-stimulated endometrium.

12. POSTHUMUS RG. [The use and the possibilities of progesterone in the treatment of glaucoma]. Ophthalmologica. 1952 Jul;124(1):17-25. Undetermined Language. doi: 10.1159/000301245. PMID: 12983046.

4.8
Rated 4.8 out of 5 stars
Based on 21 reviews
Total 5 star reviews: 18 Total 4 star reviews: 2 Total 3 star reviews: 0 Total 2 star reviews: 1 Total 1 star reviews: 0
95%would recommend this product
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21 reviews
  • TW
    Taylor W.
    Verified Buyer
    I recommend this product
    How old are you? 18-24
    What is your gender? Female
    Rated 5 out of 5 stars
    6 months ago
    Highest Quality OTC Progesterone

    This progesterone supplement raised my urine PdG (a metabolite of progesterone that tends to track fairly well with serum progesterone levels) from 2.58 ug/ml to 16.22 in ONE DAY, the highest it’s ever been. This took me from way below what I needed, passed the minimum of 10, and well into the “ideal” range! That said, ultimately I did have to go with prescription progesterone unfortunately because of the severity of my body’s need for progesterone right now. But, we trust this product more for quality and purity, so we were sad to part with it. Just needed a much higher dose for our immediate needs right now. If I ever need to supplement with progesterone again, and I can take lower doses, this is exactly what we’ll be buying!

  • CV
    Cilsa V.
    Verified Buyer
    I recommend this product
    How old are you? 45-54
    What is your gender? Female
    Rated 5 out of 5 stars
    11 seconds ago
    Amazing!!

    This product is amazing! Swear by it :)

  • NB
    Nicola B.
    Verified Buyer
    I recommend this product
    How old are you? 45-54
    What is your gender? Female
    Rated 5 out of 5 stars
    3 weeks ago
    Awesome

    I’m 46 and started suffering from really terrible peri menopausal hot flashes and decided to try this product and within a week or so they were gone. I’ve been consistently taking it for over 6 months now as described in the bottle (6 drops in the morning/evening) and I haven’t had a return of any symptoms. I feel less stressed overall and do sleep better (I also take Lifeblud magnesium which contributes as well). It may not be the right path for every woman during this phase where hormones drop or become imbalanced but it’s certainly helped me. I won’t live without it! Thank you for this great product Adam!

  • ME
    Myriam E.
    Verified Buyer
    I recommend this product
    How old are you? 45-54
    What is your gender? Female
    Rated 5 out of 5 stars
    4 weeks ago
    Excellent Product

    Excellent Product. Immediately felt the effects! Highly recommend for anyone needed Progesterone.

  • NB
    Nanci B.
    Verified Buyer
    I do not recommend this product
    How old are you? 55-64
    What is your gender? Female
    Rated 2 out of 5 stars
    4 months ago
    Leaking

    Unfortunately, mine arrived leaking product. It has continued to leak, I’m still trying to use all of it that I can.

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