Protect
- Hormone Support
- Stress Relief
Bio-Identical Progesterone
Each bottle contains: 1 oz. (32ml)
Servings per bottle: ~75
Total progesterone per bottle: 2,700 mg.
Progesterone per drop: 3mg
Fully dissolved, high purity, molecular serum in a vitamin E and MCT oil base for optimal absorption. Derived from wild yams through an enzyme extraction process.
Third-party lab tested for purity.
Stress and anxiety reduction*
Balancing estrogen dominance*
PMS/Hormonal imbalance symptoms*
Brain and memory protective*
Sunburn/sunspots*
Skin firmness & elasticity*
Arthritis*
Tendonitis*
Bursitis*
Wound healing*
Osteoporosis*
Prostate protection*
*These Statements have not been evaluated by the Food and Drug Association, or Health Canada. These products are not meant to diagnose, treat, cure, or prevent any diseases.
Other ingredients: Mixed tocopherols, MCT oil.
*Refrigeration not necessary. Stable for 1 year after opening, 3 years if sealed.
While we are not 'allowed' to provide medical advice, menstruating women have typically used Protect cyclically, taking 6 drops twice a day orally, only between ovulation and menstruation, and not taking it from menstruation until the next ovulation.
For topical treatment of sun damaged skin, burns, acne, or wrinkles, Protect can be applied directly to the affected area.
We are unable to offer medical advice regarding the usage of progesterone, such as inquiries related to pregnancy, menopause or substituting medications. We recommend that these inquiries be directed to your medical provider for proper guidance and assistance.
1. Chishti YZ, Feswick A, Martyniuk CJ. Progesterone increases ex vivo testosterone production and decreases the expression of progestin receptors and steroidogenic enzymes in the fathead minnow (Pimephales promelas) ovary. Gen Comp Endocrinol. 2014 Apr 1;199:16-25. doi: 10.1016/j.ygcen.2014.01.004. Epub 2014 Jan 21. PMID: 24462459.
2. Mohammed H, Russell IA, Stark R, et al. Progesterone receptor modulates ERα action in breast cancer [published correction appears in Nature. 2015 Oct 1;526(7571):144. Serandour, Aurelien A A[Corrected to Serandour, Aurelien A]]. Nature. 2015;523(7560):313-317. doi:10.1038/nature14583
3. Stanczyk FZ. Treatment of postmenopausal women with topical progesterone creams and gels: are they effective? Climacteric. 2014 Dec;17 Suppl 2:8-11. doi: 10.3109/13697137.2014.944496. Epub 2014 Sep 6. PMID: 25196424.
4. Smith SS. Progesterone administration attenuates excitatory amino acid responses of cerebellar Purkinje cells. Neuroscience. 1991;42(2):309-20. doi: 10.1016/0306-4522(91)90377-z. PMID: 1654533.
5. El-Etr M, Rame M, Boucher C, et al. Progesterone and nestorone promote myelin regeneration in chronic demyelinating lesions of corpus callosum and cerebral cortex. Glia. 2015;63(1):104-117. doi:10.1002/glia.22736
6. Formby B, Wiley TS. Progesterone inhibits growth and induces apoptosis in breast cancer cells: inverse effects on Bcl-2 and p53. Ann Clin Lab Sci. 1998 Nov-Dec;28(6):360-9. PMID: 9846203.
7. Cowan LD, Gordis L, Tonascia JA, Jones GS. Breast cancer incidence in women with a history of progesterone deficiency. Am J Epidemiol. 1981 Aug;114(2):209-17. doi: 10.1093/oxfordjournals.aje.a113184. PMID: 7304556.
8. MEDICAL TREATMENT OF MALE PATTERN ALOPECIA (ANDROGENIC ALOPECIA)
9. Correction of hormonal imbalance in patients with diffuse forms of mastopathy – the basis of pathogenetic therapy and oncoprophylaxis
10. Brkic, M. , Vujovic, S. , Ivanisevic, M. , Ivovic, M. , Gajic, M. , Marina, L. , Barac, M. , Barac, B. , Djogo, A. , Malesevic, G. and Franic, D. (2016) The Influence of Progesterone Gel Therapy in the Treatment of Fibrocystic Breast Disease. Open Journal of Obstetrics and Gynecology, 6, 334-341. doi: 10.4236/ojog.2016.65042.
11. Topical progesterone cream has an antiproliferative effect on estrogen-stimulated endometrium.
12. POSTHUMUS RG. [The use and the possibilities of progesterone in the treatment of glaucoma]. Ophthalmologica. 1952 Jul;124(1):17-25. Undetermined Language. doi: 10.1159/000301245. PMID: 12983046.
Protect Background Information
Mainly - progesterone is anti-cortisol and anti-estrogen.
Progesterone is the primary hormone for adaptation and resistance to stress. Adequate amounts of progesterone in the body prevent the excess production of cortisol, one of our primary stress hormones. This is because progesterone inhibits enzymes that increase the production of estrogen, serotonin, and histamine and decreases enzymes that promote excitatory neurotransmitters such as ACTH and NMDA, which can contribute to stress and anxiety.
Progesterone is primarily associated with the female reproductive system. Its central role revolves around preparing the uterus for pregnancy and supporting early pregnancy development. During the menstrual cycle, progesterone levels rise after ovulation, helping to thicken the uterine lining in anticipation of embryo implantation. If pregnancy doesn't occur, progesterone levels decrease, leading to menstruation.
However, progesterone is much more than just a hormone that facilitates pregnancy. Having sufficient levels is crucial for resilience from stress, relieving anxiety, improving memory, protecting brain cells, and contributing to bone and skin health.
Progesterone can also protect against the toxic effects of excess estrogen, leading to symptoms such as acne, stubborn weight gain, depression/anxiety, breast tenderness, cramping, and more, as experienced in PMS, Endometriosis, PCOS, and so forth.
Progesterone is not only produced in women but is also important in men as it is required for testosterone production, bone health, and prostate health. It protects the overall structure of tissues and prevents their degradation. Progesterone deficiency is less common in men, but supplementation can be helpful in times of increased stress/trauma.

Protect
- TWTaylor W.Verified BuyerI recommend this productHow old are you? 18-24What is your gender? FemaleRated 5 out of 5 stars2 years agoHighest Quality OTC Progesterone
This progesterone supplement raised my urine PdG (a metabolite of progesterone that tends to track fairly well with serum progesterone levels) from 2.58 ug/ml to 16.22 in ONE DAY, the highest it’s ever been. This took me from way below what I needed, passed the minimum of 10, and well into the “ideal” range! That said, ultimately I did have to go with prescription progesterone unfortunately because of the severity of my body’s need for progesterone right now. But, we trust this product more for quality and purity, so we were sad to part with it. Just needed a much higher dose for our immediate needs right now. If I ever need to supplement with progesterone again, and I can take lower doses, this is exactly what we’ll be buying!
Was this helpful? - JGJacqueline G.Verified BuyerI recommend this productRated 5 out of 5 stars2 days agoJust bought my second bottle
Beautiful product, probably will never be without it again if I can help it. My body breathes a sigh of relief when I take it and putting it in my skin makes me more beautiful.
Was this helpful? - NGNadia G.Verified BuyerI recommend this productRated 5 out of 5 stars1 week agoLife Saver ( not being hyperbolic)
I was on pregnenalone for years but around the time my menses stopped I really could see I was autistic my entire life. I could no longer mask or cope with much ans I once did and my sleep was destroyed and hot flashes and I aged overnight. ( okay that’s was hyperbolic). I started slow but after a few years I take quite a bit as it’s restored so much for me including my immunity. My skin is beautiful and I’m radiant . I use a lot of the other supplements from lifeblud and follow Ray Peat principles since learning about Dr Raymond Peats work in 2008. I like knowing that Adam knows about Rays endocrine and biology background because his supplements all support a prometabolic lifestyle and are part of Rays suggestions. Thank you Adam for your top notch supplements. Easy free shipping to Canada and I wouldn’t want to be without lifebluds supplements and wonderful knowledge attached to each product. Thank you for the best friendly and responsive customer service too!
Was this helpful? - CICarson I.Verified BuyerI recommend this productRated 5 out of 5 stars1 week agoGreat
Great product. Makes me feel warm and fuzzy and kicks pms to the curb. I also use some topically on lips and wrinkles around eyes and have been looking more youthful
Was this helpful? - JSJonathon S.Verified BuyerI recommend this productRated 5 out of 5 stars2 weeks agoWonderful SLEEP aid
I know that for men in general, progesterone tends to bring on sleepiness. I take 6 drops and night and noticed a significant difference in how fast I fell asleep & how much more refreshed I felt in the morning. Additionally I usually get up once to use the bathroom and would often have trouble falling back asleep. But this has made a huge difference with even this, where I hardly recall getting up.
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