TUDCA & Ox Bile

TUDCA MAX

$56.00 USD
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19 reviews

TUDCA & Ox Bile Extract capsules

Synthesized TUDCA, combined with Ox Bile extract in a bovine gelatin capsule.

Tauroursodeoxycholic acid (TUDCA) is a water-soluble, conjugated bile salt. It is produced in the liver using cholesterol, deoxycholate (which is made in the intestine by bacteria and cholic acid), and the amino acid Taurine. Supplementing with TUDCA can aid digestion, liver health and detoxification by increasing bile flow and clearing out sludgy bile.

Third-party tested for purity. 

Supplement Facts

Each bottle contains: 60 capsules
Servings per container
: 30

Each capsule contains:
Tauroursodeoxycholic Acid (TUDCA): 250mg
Ox Bile Extract (45% Cholic Acid): 50mg 

Other ingredients: Gelatin (bovine), NuFlow (rice hull). 

Benefits

  • Liver support & detox*
  • Improved bile flow*
  • Improved fat digestion*
  • Increased fat-soluble vitamin absorption*
  • Supports gut health*
  • Aids in toxin elimination via bile*
  • Neuroprotective *
  • May assist in dissolving gallstones*
  • May improve liver and muscle insulin sensitivity*
  • May reduce elevated liver enzyme markers*
  • May lower cholesterol*
  • May reduce cholestasis *
  • May improve conditions of liver cirrhosis, fatty liver, and hepatitis*

*These statements have not been evaluated by the Food and Drug Association or Health Canada. These products are not meant to diagnose, treat, cure, or prevent any diseases.

How to Take

Generally, the serving size should be taken on a relatively empty stomach. For some, this can be an hour or two after a meal. Some people may also fare better with taking it well before eating, for example first thing in the morning, 30+ minutes prior to breakfast. It can be split into 2 separate doses throughout the day if desired.

The reasoning for this is because bile salts are highly alkaline, and are excreted into the intestine after our food has been acidified by stomach acid. The combination between the acidified food, and the alkaline bile salts are what create the digestion of food, fats, and absorption of vitamins (think of adding baking soda to vinegar). We want to wait to give the food enough time to be acidified, before adding in the alkaline bile salts. However, each person is different, and therefore we recommend each person find their optimal dosing and timing methods.

TUDCA is made in small amounts in humans and larger amounts in bears and other animals such as bovines. TUDCA, taken directly from Bear Bile, has been used in Traditional Chinese Medicine for centuries to improve eye health.

While bile acids are known as mild surfactants, amino-acid-conjugated bile salts like TUDCA are considered strong surfactants. This is in relation to their action as detergents for removing stuck and sludgy bile, emulsifying and helping us digest fats, and increasing bile flow from the gallbladder into the intestine.

The therapeutic value of TUDCA centers around its ability to improve bile flow. When we eliminate stuck, old, sludgy bile and improve the flow of bile, the entire metabolic function of the body is improved.

The liver becomes less congested and thus is able to perform its crucial tasks more efficiently. Fat-soluble vitamins are absorbed better, glucose from food intake is converted more efficiently into energy, digestion is improved, and ingested and stored toxins are eliminated more readily via bile.

Since 80% of thyroid hormone T3 is converted from T4 in the liver, thyroid function is accelerated with the ingestion of TUDCA, thus improving liver function. This becomes a positive feedback loop because improved thyroid function will, in turn, improve metabolism, digestion, and overall energetic function.

TUDCA and Today's Context:

Understanding the widespread liver dysfunction epidemic gives us great insight into the usefulness and therapeutic value of TUDCA supplementation. The epidemic includes highly processed food products, a seed and vegetable oil-ridden food supply, pesticides, chemical home and commercial cleaning products, alcohol overconsumption, pharmaceutical prescription drugs, ubiquitous xenoestrogens, polluted air and water, and much more.

All of these toxins we come into contact with must be processed and deactivated by our liver. The liver packages much of them into the bile, which is then excreted via the stool. 

But when we are constantly faced with an onslaught of toxins, the liver can become overburdened. When this happens, the bile flow can slow down, and both bile and cholesterol will accumulate, become sludgy, and form stones that cause congestion in the liver ducts and gallbladder.

This process, over time, causes many of the conventional diseases we are familiar with, such as high cholesterol, low thyroid, elevated liver enzymes, low metabolic function, fatty liver, and fibrosis. Furthermore, when the body's #1 detox mechanism is now impaired, it must store the toxins elsewhere, typically in the fat tissue. This creates a domino effect of stubborn obesity and overall physical toxemia. The body, as one holistic system, then begins to fall further into a state of disease. 

Restoring bile flow and liver function is of the absolute top priority for anyone who has lived through modern contexts such as these. Why add Ox Bile? Ox Bile provides a full spectrum of bile salts to round out the profile of the supplement, so that the body isn't taking in one and only one type of bile salt. Ox Bile has been used therapeutically for a very long time and may benefit those without a gallbladder, or those with insufficient bile production. 

1. Crosignani A, Battezzati PM, Setchell KD, Invernizzi P, Covini G, Zuin M, Podda M. Tauroursodeoxycholic acid for treatment of primary biliary cirrhosis. A dose-response study. Dig Dis Sci. 1996 Apr;41(4):809-15. doi: 10.1007/BF02213140. PMID: 8674405.

2.  Kars M, Yang L, Gregor MF, Mohammed BS, Pietka TA, Finck BN, Patterson BW, Horton JD, Mittendorfer B, Hotamisligil GS, Klein S. Tauroursodeoxycholic Acid may improve liver and muscle but not adipose tissue insulin sensitivity in obese men and women. Diabetes. 2010 Aug;59(8):1899-905. doi: 10.2337/db10-0308. Epub 2010 Jun 3. PMID: 20522594; PMCID: PMC2911053.

3. da-Silva WS, Ribich S, Arrojo e Drigo R, Castillo M, Patti ME, Bianco AC. The chemical chaperones tauroursodeoxycholic and 4-phenylbutyric acid accelerate thyroid hormone activation and energy expenditure. FEBS Lett. 2011 Feb 4;585(3):539-44. doi: 10.1016/j.febslet.2010.12.044. Epub 2011 Jan 14. PMID: 21237159; PMCID: PMC3133948.

4. Kusaczuk M. Tauroursodeoxycholate-Bile Acid with Chaperoning Activity: Molecular and Cellular Effects and Therapeutic Perspectives. Cells. 2019 Nov 20;8(12):1471. doi: 10.3390/cells8121471. PMID: 31757001; PMCID: PMC6952947.

5. Vang S, Longley K, Steer CJ, Low WC. The Unexpected Uses of Urso- and Tauroursodeoxycholic Acid in the Treatment of Non-liver Diseases. Glob Adv Health Med. 2014 May;3(3):58-69. doi: 10.7453/gahmj.2014.017. PMID: 24891994; PMCID: PMC4030606.

6. Cabrera D, Arab JP, Arrese M. UDCA, NorUDCA, and TUDCA in Liver Diseases: A Review of Their Mechanisms of Action and Clinical Applications. Handb Exp Pharmacol. 2019;256:237-264. doi: 10.1007/164_2019_241. PMID: 31236688.

7. Song M, Zhang F, Fu Y, Yi X, Feng S, Liu Z, Deng D, Yang Q, Yu M, Zhu C, Zhu X, Wang L, Gao P, Shu G, Ma X, Jiang Q, Wang S. Tauroursodeoxycholic acid (TUDCA) improves intestinal barrier function associated with TGR5-MLCK pathway and the alteration of serum metabolites and gut bacteria in weaned piglets. J Anim Sci Biotechnol. 2022 Jun 8;13(1):73. doi: 10.1186/s40104-022-00713-3. PMID: 35672805; PMCID: PMC9175448.

8. Tronstad RR, Berland S, Tjora E, El Jellas K, Aukrust I, Kristensen K, Tveitnes D, Molven A, Marschall HU, Rao A, Dawson PA. Fat Malabsorption and Ursodeoxycholic Acid Treatment in Children With Reduced Organic Solute Transporter-α (SLC51A) Expression. JPGN Rep. 2022 Aug;3(3):e229. doi: 10.1097/pg9.0000000000000229. Epub 2022 Jul 25. PMID: 36148443; PMCID: PMC9491403.

9. Zangerolamo L, Vettorazzi JF, Rosa LRO, Carneiro EM, Barbosa HCL. The bile acid TUDCA and neurodegenerative disorders: An overview. Life Sci. 2021 May 1;272:119252. doi: 10.1016/j.lfs.2021.119252. Epub 2021 Feb 23. PMID: 33636170.

10. Boatright JH, Nickerson JM, Moring AG, Pardue MT. Bile acids in treatment of ocular disease. J Ocul Biol Dis Infor. 2009 Sep;2(3):149-159. doi: 10.1007/s12177-009-9030-x. Epub 2009 Aug 27. PMID: 20046852; PMCID: PMC2798994.

5.0
Rated 5.0 out of 5 stars
Based on 19 reviews
Total 5 star reviews: 19 Total 4 star reviews: 0 Total 3 star reviews: 0 Total 2 star reviews: 0 Total 1 star reviews: 0
100%would recommend this product
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19 reviews
  • DB Profile picture for Deena B.
    Deena B.
    Verified Buyer
    I recommend this product
    How old are you? 45-54
    What is your gender? Female
    Rated 5 out of 5 stars
    2 months ago
    Pain Reliever

    I wanted to try this product our for a few months then take a break. I began taking to see if it would help with some medically unresolved pain I was having in my gallbladder area. After several scans and tests I was told my gallbladder was emptying fine - but still so much pain. I gave this a try for about 3 months - I found it helped, so I stopped taking it. After about another 3 weeks or so I noticed the pain was more frequent and stronger. I bought another bottle and began taking 2 capsules each morning on an empty stomach. That was about 2 weeks ago now, and I must say I am in much less discomfort , and having less off it. I am certain it is because of this product, Tudca Max.

  • A
    Allison
    Verified Buyer
    I recommend this product
    How old are you? 35-44
    What is your gender? Female
    Rated 5 out of 5 stars
    12 seconds ago
    My new favourite supplement

    This is probably the most impactful supplement I have ever taken. I have had discomfort in my right side in the liver/gallbladder region for over a year. Within 2 weeks of taking 1 Tudca in the morning and 1 in the afternoon (about 30 minutes before eating), all discomfort is gone.

  • S
    Sam
    Verified Buyer
    I recommend this product
    How old are you? 25-34
    What is your gender? Female
    Rated 5 out of 5 stars
    15 hours ago
    My new fav supplement

    I very rarely leave reviews but I have been combining this with liver flushing and the results have been incredible. Digestion and eliminations have also improved immensely. I am so grateful for this supplement with where I'm at in my liver healing journey while getting to the root cause. 2 capsules 20 min before breakfast has been perfect for me.

  • ME
    Myriam E.
    Verified Buyer
    I recommend this product
    How old are you? 45-54
    What is your gender? Female
    Rated 5 out of 5 stars
    1 month ago
    TUDCA 👍👍👍

    Love the TUDCA! Great product!

  • BG
    Bruce G.
    Verified Buyer
    I recommend this product
    How old are you? 55-64
    What is your gender? Male
    Rated 5 out of 5 stars
    1 month ago
    Good stuff

    Love it. I have had great results. I am very happy with the Tudca.

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