L-Theanine

Thea

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9 reviews

Theanine Capsules

L-Theanine (99+% purity) in a bovine gelatin capsule. Nothing else. 

L-Theanine is typically known for its benefits on focus, relaxation, memory, and calm alertness. While these benefits are pretty well documented and enjoyed by many, there is actually more to this great Theanine story, check the product background tab to learn more.

Third-party lab-tested for purity.

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Supplement Facts

Each bottle contains: 90 capsules
Servings per container: 90

Each capsule contains: L-Theanine: 500mg

Other ingredients: gelatin (bovine)
Benefits

  • Stress management*
  • Calm attentiveness*
  • Focus and Memory*
  • Mood elevation*
  • Regulation of caffeine overstimulation*
  • Neuroprotection*
  • Liver protection*
  • Bile acid regulation*
  • Improved lipid metabolism*

*These Statements have not been evaluated by the Food and Drug Association, or Health Canada. These products are not meant to diagnose, treat, cure, or prevent any diseases.
How to Take

Take 1 capsule daily, with or without food, at any time of day.

Can be beneficial to take in conjunction with caffeinated beverages to avoid caffeine overstimulation & crash.

L-Theanine - more than just a relaxation amino acid

L-Theanine is typically known for its benefits on focus, relaxation, memory, and calm alertness. While these benefits are well documented and enjoyed by many, there is more to this great Theanine story. 

Theanine, an abundant amino acid found predominantly in green tea, has also been found to lower cholesterol, regulate bile acid, protect the liver, improve metabolic function, and prevent obesity (sources in the references section below). 

Now, back to the cognitive benefits. Instead of regurgitating the same old story, we'll start with some quotes from one of our most significant influences, the late and great Dr. Ray Peat. 

"The tea amino acid, theanine, suppresses serotonin by supporting the effects of GABA."

Further

"The GABA system restrains the production of cortisol, which is typically increased in depression. GABA-supporting drugs that had been used to treat epilepsy are turning out to have anti-depressive, mood-elevating effects."

"Drugs (such as piracetam) that promote GABA's effects are called "nootropins," or cognitive enhancers, and have been used to treat brain damage and mental retardation."

Ray deeply understood the interplay between these hormonal and neurotransmitter systems, which is how he synthesized Theanine's benefit through his knowledge of GABA, serotonin, and glutamate (from his May 2008 newsletter: The GABA System, defenses, and tissue renewal). This provides us with a novel perspective on how Theanine may be able to achieve its benefits on cognition, memory, mood, focus, relaxation, and neuroprotection.

Next, its benefits on the liver are documented but seldom discussed. Two studies specifically show that L-theanine prevents alcoholic liver injury by increasing the antioxidant capacity of liver tissue, slows liver aging by reversing inflammation and oxidative stress, and inhibits advanced glycation end-products. 

A third study showed protective effects on acute liver injury by normalizing the hypothalamus-pituitary-adrenal (HPA) axis hyperactivity and lowering lipopolysaccharide-induced inflammatory response markers such as C-reactive protein, nitric oxide, TNF-A, and IL-10.

1. Wang D, Gao Q, Zhao G, Kan Z, Wang X, Wang H, Huang J, Wang T, Qian F, Ho CT, Wang Y. Protective Effect and Mechanism of Theanine on Lipopolysaccharide-Induced Inflammation and Acute Liver Injury in Mice. J Agric Food Chem. 2018 Jul 25;66(29):7674-7683. doi: 10.1021/acs.jafc.8b02293. Epub 2018 Jul 12. PMID: 29969892.



2. Li G, Ye Y, Kang J, Yao X, Zhang Y, Jiang W, Gao M, Dai Y, Xin Y, Wang Q, Yin Z, Luo L. l-Theanine prevents alcoholic liver injury through enhancing the antioxidant capability of hepatocytes. Food Chem Toxicol. 2012 Feb;50(2):363-72. doi: 10.1016/j.fct.2011.10.036. Epub 2011 Oct 14. PMID: 22019691.



3. Li MY, Liu HY, Wu DT, Kenaan A, Geng F, Li HB, Gunaratne A, Li H, Gan RY. L-Theanine: A Unique Functional Amino Acid in Tea (Camellia sinensis L.) With Multiple Health Benefits and Food Applications. Front Nutr. 2022 Apr 4;9:853846. doi: 10.3389/fnut.2022.853846. PMID: 35445053; PMCID: PMC9014247.

4. Liang J, Gu L, Liu X, Yan X, Bi X, Fan X, Zhou J, Lu S, Luo L, Yin Z. L-theanine prevents progression of nonalcoholic hepatic steatosis by regulating hepatocyte lipid metabolic pathways via the CaMKKβ-AMPK signaling pathway. Nutr Metab (Lond). 2022 Apr 15;19(1):29. doi: 10.1186/s12986-022-00664-6. PMID: 35428314; PMCID:

PMC9013079.

5. Zeng L, Lin L, Peng Y, Yuan D, Zhang S, Gong Z, Xiao W. l-Theanine attenuates liver aging by inhibiting advanced glycation end products in d-galactose-induced rats and reversing an imbalance of oxidative stress and inflammation. Exp Gerontol. 2020 Mar;131:110823. doi: 10.1016/j.exger.2019.110823. Epub 2019 Dec 31. PMID: 31899338.



6. Unno K, Iguchi K, Tanida N, Fujitani K, Takamori N, Yamamoto H, Ishii N, Nagano H, Nagashima T, Hara A, Shimoi K, Hoshino M. Ingestion of theanine, an amino acid in tea, suppresses psychosocial stress in mice. Exp Physiol. 2013 Jan;98(1):290-303. doi: 10.1113/expphysiol.2012.065532. Epub 2012 Jun 15. PMID: 22707502.



7. Peng WQ, Xiao G, Li BY, Guo YY, Guo L, Tang QQ. l-Theanine Activates the Browning of White Adipose Tissue Through the AMPK/α-Ketoglutarate/Prdm16 Axis and Ameliorates Diet-Induced Obesity in Mice. Diabetes. 2021 Jul;70(7):1458-1472. doi: 10.2337/db20-1210. Epub 2021 Apr 16. PMID: 33863801.

8. Yang L, Zhang L, Zhang P, Zhou Y, Huang X, Yan Q, Tan Z, Tang S, Wan F. Alterations in nutrient digestibility and performance of heat-stressed dairy cows by dietary L-theanine supplementation. Anim Nutr. 2022 Aug 11;11:350-358. doi: 10.1016/j.aninu.2022.08.002. PMID: 36329682; PMCID: PMC9618971.



9. Xu W, Kong Y, Zhang T, Gong Z, Xiao W. L-Theanine regulates lipid metabolism by modulating gut microbiota and bile acid metabolism. J Sci Food Agric. 2023 Feb;103(3):1283-1293. doi: 10.1002/jsfa.12222. Epub 2022 Sep 23. PMID: 36087337.



10. Zhang G, Miura Y, Yagasaki K. Effects of dietary powdered green tea and theanine on tumor growth and endogenous hyperlipidemia in hepatoma-bearing rats. Biosci Biotechnol Biochem. 2002 Apr;66(4):711-6. doi: 10.1271/bbb.66.711. PMID: 12036040.



*These statements are not approved or regulated by the FDA or Health Canada. 
5.0
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9 reviews
  • S
    Sam
    Verified Buyer
    I recommend this product
    Rated 5 out of 5 stars
    12 seconds ago
    The best

    One of the most effective supplements I have- I can literally feel my stress levels come down when I take it and it happens immediately. I also love the liver supporting effects. Highly recommend!

    Was this helpful?
  • CC
    Char C.
    Verified Buyer
    I recommend this product
    Rated 5 out of 5 stars
    4 weeks ago
    Great!!

    Will order again!!

    Was this helpful?
  • J
    Joseph
    I recommend this product
    Rated 5 out of 5 stars
    2 months ago
    5 Stars

    Awesome

    Was this helpful?
  • K
    Kai
    Verified Buyer
    I recommend this product
    How old are you? 25-34
    What is your gender? Female
    Rated 5 out of 5 stars
    3 months ago
    THEA

    So far I have been having great results.

    Was this helpful?
  • JM
    Judy M.
    Verified Buyer
    I recommend this product
    How old are you? Over 65
    What is your gender? Female
    Rated 5 out of 5 stars
    4 months ago
    Thea

    I’ve been taking the 3 amino acids for a few months and I find that I am less stressed, I sleep better, I am glad I’m taking them

    Was this helpful?
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